Mohammad‐Reza Ghovanloo

Combinatorial logic of Nav channels in nociceptor excitability: Different degrees of synergy define distinct neuronal groups

The paper investigates how combinations of Nav1.7 and Nav1.8 channels affect nociceptor excitability, showing that their synergistic effects vary across neuronal subtypes.

Targeted ubiquitination of NaV1.8 reduces sensory neuronal excitability

This study develops a therapeutic protein, UbiquiNaV, that reduces NaV1.8 channel expression in sensory neurons, alleviating pain in preclinical models.