A computational framework for systematic exploration of biosynthetic diversity from large-scale genomic data
Jorge Carlos Navarro-Muñoz, Nelly Selem Mojica, Michael W. Mullowney, Satria Ardhe Kautsar, James H. Tryon, Elizabeth I. Parkinson, Emmanuel L. C. de los Santos, Marley Yeong, Pablo Cruz‐Morales, Sahar Abubucker, Arne Roeters, Wouter Lokhorst, Antonio Fernàndez-Guerra, Luciana Teresa Dias Cappelini, Anthony W. Goering, , Marnix H. Medema
The paper introduces two tools, BiG-SCAPE and CORASON, for analyzing biosynthetic gene clusters in large genomic datasets, demonstrating their utility through validation and discovery of new gene cluster families.
Nature Chemical Biology · Nov 25, 2019Peer-reviewedBioinformatics