Repurposing the HMG-CoA Reductase Inhibitor Atorvastatin for SRD5A3-CDG
Hiba Daghar, Seul Kee Byeon, Claudia Maios, Jennifer Yuen Ying Poon, James J Doyle, Wasantha K. Ranatunga, Éric Samarut, Ethan O. Perlstein, Éva Morava, Akhilesh Pandey, J. Alex Parker, Kristin A. Kantautas
The paper develops a C. elegans model of SRD5A3-CDG and identifies atorvastatin as a potential repurposed therapy through a high-throughput screen.
bioRxiv · Jan 20, 2026 · PreprintCell Biology