Claudia Maios

The paper develops a zebrafish C9orf72 knockout model for ALS, identifies pizotifen malate as a potential therapeutic, and validates its efficacy in both zebrafish and C. elegans models.

The paper develops a C. elegans model of SRD5A3-CDG and identifies atorvastatin as a potential repurposed therapy through a high-throughput screen.

This paper introduces a new drug-like small molecule series targeting PDI in a multi-protein complex for ALS treatment, showing activity in cellular and animal models.

This study shows that overexpressing tau variants in C. elegans motor neurons causes neuronal and peripheral defects, suggesting tau dysfunction disrupts cell-cell communication.