Engineered Serum Markers for Noninvasive Monitoring of Gene Expression in the Brain
Sangsin Lee, Shirin Nouraein, James J. Kwon, Zhimin Huang, Jessica A. Wojick, Boao Xia, Gregory F. Corder, Jerzy O. Szablowski
This paper introduces a noninvasive method to monitor brain gene expression using engineered reporters called RMAs, which detect neuronal activity through blood measurements.
Nature Biotechnology · Jan 10, 2024Peer-reviewedNeuroscience