Gregory F. Corder

The paper identifies a specific neural circuit between the ACC and dlPAG that facilitates the affective component of pain, showing its role in aversive behaviors beyond pain.

The paper uses calcium imaging in mice to show that the retrosplenial cortex flexibly reorganizes during shock prediction, while the anterior cingulate cortex encodes ongoing nociception and defensive behavior.

The paper identifies a functional dichotomy in the ventrolateral periaqueductal gray, showing that micro opioid receptor neurons encode nociceptive states while enkephalin-releasing neurons drive pain relief in various contexts.

The paper identifies a cortical circuit in mice modulated by opioids and develops a gene therapy to mimic opioid analgesia for chronic pain.

This study identifies PKCδ neurons in the central amygdala as key mediators of fentanyl withdrawal by showing their hyperactivity and role in withdrawal signs.

This paper creates an anatomical and molecular atlas of the nociceptive medial thalamus, identifying a distinct population of opioid receptor-expressing neurons involved in pain processing.

The paper develops a behavioral analysis pipeline using LUPE to quantify opioid withdrawal behaviors in mice, identifying challenges in capturing rapid behaviors and laying groundwork for standardized quantification.

This study shows psilocybin enhances fear extinction by altering cortical neural ensembles, with acute suppression of fear-active neurons and delayed recruitment of extinction-active neurons.

AxoDen quantifies axonal density in defined brain regions using a semi-automated platform to improve accuracy and reduce variability compared to traditional methods.

This study identifies VTAMOR neurons as critical modulators of low sociability during protracted opioid withdrawal and highlights their potential as a therapeutic target.

This study identifies a BLAnoci ensemble in the basolateral amygdala that mediates both acute and chronic pain behavior through a novel amygdala-striatal circuit involving the nucleus accumbens shell.

This paper introduces a noninvasive method to monitor brain gene expression using engineered reporters called RMAs, which detect neuronal activity through blood measurements.

This paper introduces PAWS, a machine-vision tool for automated pain measurement in mice, showing it can distinguish painful from non-painful stimuli and quantify pain severity.