Author

James L C Che

Wellcome/MRC Cambridge Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. Hogg· 1 shared Alyssa H. CulliD· 1 shared Andrew N. HoldingiD· 1 shared Bart TheeuwesiD· 1 shared Benjamin A. HalliD· 1 shared Berthold GöttgensiD· 1 shared Daniel BodeiD· 1 shared David G. KentiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alexander J. Hogg

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1 paper

Recent·Most cited

Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules

Maria Jassinskaja, Daniel Bode, Monika Gońka, Theodoros I. Roumeliotis, Alexander J. Hogg, Juan A Rubio Lara, Ellie Bennett, Joanna Milek, Bart Theeuwes, M. S. Vijayabaskar, Lilia Cabrera-Cosme, James L C Che, Sandy J. Macdonald, Sophia Ahmed, Benjamin A. Hall, , David G. Kent

The paper characterizes Tet2-mutant HSCs using multi-omic data and identifies ECM molecules as regulators of self-renewal in pre-leukemic HSCs.

bioRxiv · Jan 20, 2025 · PreprintCell Biology