Sandy J. Macdonald

This study develops an in vitro clonal competition model to identify preleukemic TET2-mutant clones that suppress wild-type cells through RAC1-GEF signalling inhibition.

A 3D-printed OpenFlexure Microscope adapted for humid incubators, with relocated electronics, ASA printing and 22 Ω current-limiting resistors, records 48-hour label-free docetaxel responses that CellPhe can analyse.

This study identifies DtpT as the primary dipeptide transporter in Staphylococcus aureus and reveals its role in glutathione uptake, enhancing bacterial survival in macrophages.

This study identifies the COG complex as essential for Ktd1 trafficking, which mediates resistance to the A/B toxin K28 in yeast.

This study characterizes the pathogenicity and genome of a Pythium aphanidermatum isolate causing damping-off in amaranth, revealing its virulence factors and genome assembly.

The paper characterizes Tet2-mutant HSCs using multi-omic data and identifies ECM molecules as regulators of self-renewal in pre-leukemic HSCs.