Author

James McMahon

Pfizer (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Alex BarroniD· 2 shared Kathryn BoundiD· 2 shared Thomas A. WynniD· 2 shared Thomas FabreiD· 2 shared Chang WangiD· 1 shared Christella E. WidjajaiD· 1 shared Christopher J. StairikeriD· 1 shared Christopher P. DilloniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Alex BarronORCID

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Author profile →

2 papers

Recent·Most cited

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosis

Cynthia Lebeaupin, Katelyn L. Donahue, Samir Lal, Stephen M. Christensen, Shoh M. Asano, Marc H. Wadsworth, Kathryn Bound, Saurav De, James McMahon, Franklin J. Schlerman, Chang Wang, Xiao Chen, Alex Barron, Thomas A. Wynn, Kevin M. Hart, Thomas Fabre

This study shows myeloid cells, not conventional T cells, drive fibrosis in MASH by retaining CD8 T cells in the fibrotic niche.

bioRxiv · Jan 20, 2026 · PreprintImmunology

Therapeutic Blockade of Type 2 Cytokines and PD1 Unleashes Anti-Tumor Immunity Through Coordinated Reprogramming of Innate and Adaptive Immune Surveillance

Thomas Fabre, Eleanore Hendrickson, Katherine McGourty, Paola Marcovecchio, James McMahon, Sara Patti, KaiLi Cage, Stephen C. Searles, Christella E. Widjaja, Christopher J. Stairiker, Kathryn Bound, Roxanne Martino, Edward Pyszczynski, Ying Zhang, Graham D. Thomas, , Alex Barron

This study shows that blocking type 2 cytokines and PD1 enhances anti-tumor immunity by reprogramming immune cells in both in vitro and in vivo models.

bioRxiv · Sep 26, 2025 · PreprintCancer Biology