Shoh M. Asano

This study shows myeloid cells, not conventional T cells, drive fibrosis in MASH by retaining CD8 T cells in the fibrotic niche.

The paper introduces umExM, a method for dense membrane labeling and expansion microscopy to achieve nanoscale visualization of membranes in tissues, demonstrating resolution down to ~35 nm.

This study identifies SPAG7 gene mutations in mice causing intrauterine growth restriction and adult obesity through reduced energy expenditure and mitochondrial dysfunction.

This study shows that enhancing NaV1.1 in Dravet syndrome patient neurons increases firing rates and reduces network synchrony using HD-MEAs.

The paper develops cell body-targeted calcium indicators to improve signal fidelity in one-photon imaging of neural activity in live mice and zebrafish.

The paper combines expansion and lattice light sheet microscopy to enable high-speed, nanoscale molecular imaging of neural circuits across large volumes.

This paper introduces Light Sheet Theta Microscopy (LSTM) for high-resolution quantitative imaging of large biological systems, showing it achieves superior uniform resolution compared to traditional Light Sheet Microscopy.