A Yeast Two-Hybrid Protein Domain Screening Approach for Ebola Virus-Human Protein Interactions Identifies PABPC1 as a Host Factor Required for Replication
James Patrick Connell, Venkatesh Sivanandam, Sarah Hulsey Stubbs, Callie J. Donahue, Veronica J Heintz, Bruno La Rosa, Olena Shtanko, Robert A. Davey, Douglas J. LaCount
This paper uses yeast two-hybrid screens to identify EBOV-human protein interactions, revealing PABPC1 as a host factor required for viral replication.
bioRxiv · Mar 5, 2026 · PreprintMicrobiology