Author

Callie J. Donahue

Boston UniversityORCID 0000-0002-4284-2914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Robert A. DaveyiD· 2 shared Benyapa KhowpinitchaiiD· 1 shared Bruno La Rosa· 1 shared Christopher A. CassaiD· 1 shared Douglas J. LaCountiD· 1 shared Ersin AkıncıiD· 1 shared Grace Hui Ting YeoiD· 1 shared Heysol C. Bermudez-Cabrera· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Robert A. DaveyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A Yeast Two-Hybrid Protein Domain Screening Approach for Ebola Virus-Human Protein Interactions Identifies PABPC1 as a Host Factor Required for Replication

James Patrick Connell, Venkatesh Sivanandam, Sarah Hulsey Stubbs, Callie J. Donahue, Veronica J Heintz, Bruno La Rosa, Olena Shtanko, Robert A. Davey, Douglas J. LaCount

This paper uses yeast two-hybrid screens to identify EBOV-human protein interactions, revealing PABPC1 as a host factor required for viral replication.

bioRxiv · Mar 5, 2026 · PreprintMicrobiology

Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics

Ersin Akıncı, Minsun Cha, Lin Lin, Grace Hui Ting Yeo, Marisa C. Hamilton, Callie J. Donahue, Heysol C. Bermudez-Cabrera, Larissa Cardoso Zanetti, Maggie Chen, Sammy A. Barkal, Benyapa Khowpinitchai, Nam Ky Chu, Minja Velimirovic, Rikita Jodhani, James D. Fife, , Richard I. Sherwood

This study identifies genetic pathways involved in remdesivir cytotoxicity using CRISPR-Cas9 screening and transcriptomics, finding that SLC29A3 and AK2 are key factors in toxicity and efficacy.

bioRxiv · Aug 27, 2020 · PreprintGenetics