Gli2 is necessary for migration of ventral Neural Stem Cells to demyelinated lesions
Daniel Z. Radecki, Heather M. Messling, James R. Haggerty-Skeans, Sai Krishna Bhamidipati, Elizabeth D. Clawson, Christian A. Overman, Madison M. Thatcher, James L. Salzer, Jayshree Samanta
The paper shows Gli2 is essential for migration of ventral neural stem cells to demyelinated lesions and their differentiation into oligodendrocytes, highlighting the non-redundant roles of Gli1 and Gli2 in remyelination.
Stem Cell Reports · Oct 30, 2020Peer-reviewedNeuroscience