James L. Salzer

SnapG automates g-ratio measurement from electron micrographs, providing accurate and reproducible results with batch processing capabilities.

This study identifies Gli1's role in regulating endoneurial architecture in peripheral nerves, showing it functions independently of Dhh and is required for maintaining nerve structure.

The paper analyzes transcriptomic changes in Gli1-deficient neural stem cells during demyelination to identify mechanisms enhancing remyelination.

The paper shows Gli2 is essential for migration of ventral neural stem cells to demyelinated lesions and their differentiation into oligodendrocytes, highlighting the non-redundant roles of Gli1 and Gli2 in remyelination.

The paper shows microglia are necessary for toxin-induced demyelination and sufficient to cause demyelination independently of primary myelin damage.