A transcription-driven microgel network poised near the sol-gel transition
Mattia Marenda, Michael Chiang, Rafal Czapiewski, Davide Michieletto, Jon Stocks, Sophie Winterbourne, Jamilla Miles, Olivia Fleming, Elena Lazarova, Graeme R. Grimes, Hannes Becher, Atlanta G. Cook, Ryu‐Suke Nozawa, Davide Marenduzzo, Nick Gilbert
This paper shows that RNA and SAF-A form a microgel network in the nucleus near the sol-gel transition, exhibiting viscoelastic properties and reconciling solid-like and fluid-like behaviors.
bioRxiv · Jun 16, 2024 · PreprintMolecular Biology