Atlanta G. Cook

This study shows that Mto1 and Mto2 stabilize γ-tubulin positions in fission yeast γ-TuRCs, enabling microtubule nucleation through structural modulation.

The paper determines the structure of the apo-PIWIL4-HSP90 complex and shows it adopts an open conformation distinct from piRNA-bound PIWI.

The paper identifies a chicken MHC class II molecule that binds the same viral peptide with both nonamer and decamer core sequences, revealing binding plasticity in immune response to MDV.

This study shows that acetylation of PABPC1 at K606 enhances its affinity for eRF3a, promoting competitive recruitment and modulating mRNA fate.

This study shows that DICER1 mutations lead to increased 3p-miRNA activity, HERVH activation, and metastatic potential without causing genomic instability.

This study investigates how NF45-NF90 heterodimers bind and coat long dsRNA, revealing structural changes and implications for RNA processing.

This study identifies Pin4 as a yeast RNA-binding protein that coordinates post-transcriptional and transcriptional responses to energy depletion by regulating mRNA binding and transcriptional shifts during glucose withdrawal.

This study identifies SID-2 as an extracellular vesicle protein in parasitic nematodes that does not function in environmental RNAi, suggesting a shift in its ancestral role.

This paper shows that RNA and SAF-A form a microgel network in the nucleus near the sol-gel transition, exhibiting viscoelastic properties and reconciling solid-like and fluid-like behaviors.

This study identifies a network of DZF proteins that regulate alternative splicing through dsRNA binding and reveals their roles in splicing fidelity and cassette exon regulation.

The paper uses missense variant depletion patterns to identify functional sites in ARID family proteins and reveals sub-functionalization through domain-level comparisons.

The paper identifies SALL4 as a protein that interprets DNA base composition by binding to AT-rich motifs, and shows its role in controlling cell fate through regulation of AT-rich gene expression.

The paper shows how inactive pseudonucleases in fungi evolved from active Dis3L2 enzymes, retaining non-nuclease functions across lineages.