Prolyl isomerase FKBP12 reduces axon growth and negatively regulates microtubule polymerization by inhibiting CRMP2A
Romana Weissová, Jan Sabo, Djamel Eddine Chafai, Jakub Žiak, Peter Buran, Satish Bodakuntla, Carsten Janke, Zdeněk Lánský, Martin Balaštík
This paper shows FKBP12 inhibits CRMP2A-mediated microtubule polymerization and axon growth by binding to unphosphorylated CRMP2A.
bioRxiv · Jan 13, 2025 · PreprintNeuroscience