Somatic copy number variant load in neurons of healthy controls and Alzheimer's disease patients
Zeliha Gözde Turan, Vincent Richter, Jana Bochmann, Poorya Parvizi, Etka Yapar, Ulaş Işıldak, Sarah-Kristin Waterholter, Sabrina Leclère-Turbant, Çağdaş Devrim Son, Charles J. Duyckaerts, İdil Yet, Thomas Arendt, Mehmet Somel, Uwe Ueberham
The paper examines somatic copy number variant (CNV) frequencies in neurons from Alzheimer's disease patients and healthy controls using low-coverage single-cell whole-genome sequencing, finding slightly higher CNV frequencies in AD patients but no statistically significant differences.
Acta Neuropathologica Communications · Nov 30, 2022Peer-reviewedBioinformatics