Author

Jane Foo

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Nada LallousiD· 2 shared Anne M. HaegertiD· 1 shared Artem R CherkasoviD· 1 shared Colin C. CollinsiD· 1 shared Emirhan TekogluiD· 1 shared Jennifer M. BuiiD· 1 shared Jiaying YouiD· 1 shared Jörg A. GsponeriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Nada LallousORCID

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2 papers

Recent·Most cited

Deep Modeling of Gain of Function Mutations on Androgen Receptor

Jiaying You, Jane Foo, Nada Lallous, Artem R Cherkasov

This study uses deep modeling to predict gain-of-function mutations in the androgen receptor and their drug responses, achieving 80% accuracy in identifying agonist/antagonist relationships.

Molecular Informatics · Apr 1, 2025Peer-reviewedBioinformatics

AR-V7 condensates drive androgen-independent transcription in castration resistant prostate cancer

Shabnam Massah, Nicholas C. Pinette, Jane Foo, Sumanjit Datta, Maria Guo, Robert H. Bell, Anne M. Haegert, Emirhan Tekoglu, Mailyn Terrado, Stanislav V. Volik, Stéphane Le Bihan, Jennifer M. Bui, Nathan A. Lack, Martin Edwin Gleave, Suhn K. Rhie, , Nada Lallous

This study shows AR-V7 forms condensates independently of androgens and AR-FL in CRPC, driving oncogenic transcription through both condensate-dependent and -independent mechanisms.

bioRxiv · Jan 8, 2025 · PreprintCancer Biology