HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver
Jonathan Deans, Poonamjot Deol, Nina Titova, Sarah H. Radi, Linh M. Vuong, Jane R. Evans, Songqin Pan, Johannes Francois Fahrmann, Jun Yang, Bruce D. Hammock, Oliver Fiehn, Baharan Fekry, Kristin L Eckel‐Mahan, Frances M. Sladek
This study shows that P2-HNF4 regulates ketogenesis in the liver and is involved in circadian metabolism, with implications for gender-specific ketone body levels.
Frontiers in Endocrinology · Dec 4, 2023Peer-reviewedGenomics