Linh M. Vuong

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.

HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver

This study shows that P2-HNF4 regulates ketogenesis in the liver and is involved in circadian metabolism, with implications for gender-specific ketone body levels.

Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer

This paper designs a CDC42 effector interaction inhibitor (ARN22089) that shows anti-cancer activity by blocking tumor invasion and angiogenesis.