Author

JaNise J Jackson

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Austin Tedman· 2 shared Catherine Foye· 2 shared Charles P. KuntziD· 2 shared Jens MeileriD· 2 shared Jonathan P. SchlebachiD· 2 shared Kathryn E. OliveriD· 2 shared Lars PlateiD· 2 shared Andrew G. McKeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPharmacology & Toxicology

Austin Tedman

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2 papers

Recent·Most cited

Profiling the CFTR Variant Selectivity and Off-Target Interactions of VX-121

Ashish R. Jhangiani, John A. Olson, Austin Tedman, Catherine Foye, JaNise J Jackson, Ashlyn G Winters, J Renfrew White, Mia Perfetti, Grace M Abell, Crissey D. Cameron, Liudmyla Arifova, Brianna Corman, J. Paul Robinson, Charles P. Kuntz, Kaitlyn V. Ledwitch, , Jonathan P. Schlebach

This study evaluates VX-121's efficacy across 232 rare CFTR variants, finding it generally more effective than VX-445 but with one variant showing reduced selectivity.

bioRxiv · Jun 8, 2026 · PreprintPharmacology & Toxicology

General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR Variants

Austin Tedman, John A Olson, Minsoo Kim, Catherine Foye, JaNise J Jackson, Eli Fritz McDonald, Andrew G. McKee, Karen Noguera, Charles P. Kuntz, Jens Meiler, Kathryn E. Oliver, Lars Plate, Jonathan P. Schlebach

This study investigates how calnexin modulates the expression and pharmacological rescue of CFTR variants using deep mutational scanning, revealing its role in CFTR assembly and variant-specific corrector responses.

bioRxiv · Apr 3, 2025Biochemistry