Author

Karen Noguera

Harvard UniversityORCID 0000-0002-5037-3863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aditya M. KunjapuriD· 1 shared Andrew G. McKeeiD· 1 shared Austin Tedman· 1 shared Catherine Foye· 1 shared Charles P. KuntziD· 1 shared Daniel J. Mandell· 1 shared Eli Fritz McDonaldiD· 1 shared Eriona HysolliiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSynthetic Biology

Aditya M. KunjapurORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivApr 3, 2025

General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR Variants

Austin Tedman, John A Olson, Minsoo Kim…·Jonathan P. Schlebach

This study investigates how calnexin modulates the expression and pharmacological rescue of CFTR variants using deep mutational scanning, revealing its role in CFTR assembly and variant-specific corrector responses.

DOI 10.7554/elife.107180

humandeep learning

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Synthetic BiologyScience AdvancesPeer-reviewedJul 2, 2021

Synthetic auxotrophy remains stable after continuous evolution and in co-culture with mammalian cells

Aditya M. Kunjapur, Michael G. Napolitano, Eriona Hysolli…·George McDonald Church

The paper continuously evolves a synthetic auxotrophic E. coli strain and finds it remains contained over 100 days and in co-culture with mammalian cells.

42 citations

E. coliexperimental assay

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