Author

Jared W Green

University Medical Center Utrecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Assay:protein structure· 1

Frequent Co-Authors

Ewout J. N. GroeniD· 2 shared Fay‐Lynn AsselmaniD· 2 shared Ilaria SignoriaiD· 2 shared Joris V Kortooms· 2 shared Maria M ZwartkruisiD· 2 shared Renske I. WadmaniD· 2 shared W. Ludo van der PoliD· 2 shared Demi GommersiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Ewout J. N. GroenORCID

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2 papers

Recent·Most cited

Comprehensive analysis across SMN2 excludes DNA methylation as an epigenetic biomarker for spinal muscular atrophy

Maria M Zwartkruis, Joris V Kortooms, Demi Gommers, Martin Elferink, Ilaria Signoria, Joyce van der Sel, Paul J. Hop, Ramona A.J. Zwamborn, Robin Geene, Jared W Green, Hanneke W. M. van Deutekom, Wouter van Rheenen, Jan Herman Veldink, Fay‐Lynn Asselman, Renske I. Wadman, , Ewout J. N. Groen

This study analyzes SMN2 DNA methylation in SMA patients and finds no association with disease severity or treatment response, but identifies age-related methylation changes.

iScience · Apr 17, 2025Peer-reviewedGenetic & Genomic Medicine

Patient-specific responses to SMN2 splice-modifying treatments in spinal muscular atrophy fibroblasts

Ilaria Signoria, Maria M Zwartkruis, Lotte Geerlofs, Elena Perenthaler, Kiterie M. E. Faller, Rachel James, Harriet McHale-Owen, Jared W Green, Joris V Kortooms, Sophie H. Snellen, Fay‐Lynn Asselman, Thomas Henry Gillingwater, Gabriella Viero, Renske I. Wadman, W. Ludo van der Pol, Ewout J. N. Groen

The paper analyzes responses to SMN2 splice-modifying treatments in SMA fibroblasts, finding variability in treatment efficacy based on patient-specific factors.

Molecular Therapy — Methods & Clinical Development · Nov 13, 2024Peer-reviewedMolecular Biology