Evolution of the RNA alternative decay cis element into a high-affinity target for the immunomodulatory protein Roquin
Jan‐Niklas Tants, Katharina Friedrich, Jasmina Neumann, Andreas Schlundt
This study investigates how the RNA alternative decay element (ADE) evolved to become a high-affinity target for Roquin, revealing structural determinants and the role of a second RNA-binding interface in ADE recognition.
RNA Biology · Dec 31, 2024Peer-reviewedBiochemistry