Andreas Schlundt

The paper investigates how SMARCAD1 isoform-specific regulation affects protein dosage in ectodermal homeostasis and disease, identifying post-transcriptional and spatial mechanisms.

This paper investigates how Roquin's two ROQ domains interact with different regions of the Ox40 mRNA 3UTR, revealing opposing effects on RNA structure stability and mRNA decay.

This study investigates how the RNA alternative decay element (ADE) evolved to become a high-affinity target for Roquin, revealing structural determinants and the role of a second RNA-binding interface in ADE recognition.

This study identifies EfpL as a ribosome rescue factor that senses cellular metabolic state, complementing EF-P in proline-containing sequence translation.

This study determines the structure of the Roquin ZnF domain and shows it binds AU-rich elements, revealing how Roquin integrates RNA shape and sequence specificity through its ROQ-ZnF tandem.

This study defines Arid5a's DNA and RNA-binding preferences using biochemical and high-throughput methods, showing that disordered regions modulate its nucleic acid interactions and gene regulation.

The paper identifies the combinatorial RNA recognition code of IMP3 using an integrative approach combining SELEX-seq, iCLIP, and structural analysis.