Author

Katharina Friedrich

Goethe University FrankfurtPrimary ORCID profile (0009-0002-3566-9006 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Katharina FriedrichiD1 paper · Leibniz Institute for Neurobiology

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Organism:multiple species· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Andreas SchlundtiD· 2 shared Jan‐Niklas TantsiD· 2 shared Andreas WalbruniD· 1 shared Jasmina Neumann· 1 shared Lucas Kollwitz· 1 shared Matthias RiefiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

Andreas SchlundtORCID

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2 papers

Recent·Most cited

Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites

Jan‐Niklas Tants, Andreas Walbrun, Lucas Kollwitz, Katharina Friedrich, Matthias Rief, Andreas Schlundt

This paper investigates how Roquin's two ROQ domains interact with different regions of the Ox40 mRNA 3UTR, revealing opposing effects on RNA structure stability and mRNA decay.

Proceedings of the National Academy of Sciences · Apr 9, 2025Peer-reviewedBiophysics

Evolution of the RNA alternative decay cis element into a high-affinity target for the immunomodulatory protein Roquin

Jan‐Niklas Tants, Katharina Friedrich, Jasmina Neumann, Andreas Schlundt

This study investigates how the RNA alternative decay element (ADE) evolved to become a high-affinity target for Roquin, revealing structural determinants and the role of a second RNA-binding interface in ADE recognition.

RNA Biology · Dec 31, 2024Peer-reviewedBiochemistry