Ecdysone exerts biphasic control of regenerative signaling, coordinating the completion of regeneration with developmental progression
Faith W. Karanja, Subhshri Sahu, Sara Weintraub, Rajan Bhandari, Rebecca Garrett Jaszczak, Jason M. Sitt, Adrian Halme
The paper shows ecdysone has a dual role in Drosophila regeneration, promoting it at low concentrations and suppressing it at high concentrations, coordinating regeneration with development.
Proceedings of the National Academy of Sciences · Jan 27, 2022Peer-reviewedDevelopmental Biology