Jason T. Sengel

Dynamic exchange of antimicrobial peptides stabilize persistent lipid pores

This study uses single-molecule tracking and simulations to show that antimicrobial peptides form dynamic, persistent pores in membranes, with peptides freely diffusing into and out of the pore structure.

Orchestrating Self-Replication in Artificial Cells through Digital Microfluidics

This paper demonstrates a method using digital microfluidics to achieve autonomous DNA replication and compartment division in artificial cells, enabling genetic continuity across generations.

De novo design of α-helical peptide channels with designer stoichiometry

This paper designs and characterizes α-helical peptide channels with specific stoichiometry and conductance properties through computational and experimental methods.