De novo design of α-helical peptide channels with designer stoichiometry
Ai Niitsu, Andrew R. Thomson, Alistair J. Scott, Jason T. Sengel, Jaewoon Jung, Kozhinjampara R. Mahendran, Mikiko Sodeoka, Hagan Bayley, Yuji Sugita, Derek N. Woolfson, Mark Ian Wallace
This paper designs and characterizes α-helical peptide channels with specific stoichiometry and conductance properties through computational and experimental methods.
bioRxiv · Oct 5, 2024 · PreprintSynthetic Biology