ImmunologybioRxivPreprint
Engineering armoured in vivo CAR T cells through targeted delivery and transient mRNA gating
Kai Hu, Saket Srivastava, Biao Ma…·Shimobi C. Onuoha
This paper develops an in vivo CAR T cell platform using lipid nanoparticles and T-trex strategy to enhance safety, efficacy, and tumor control.