The E3 ubiquitin ligase RNF216 contains a linear ubiquitin chain-determining-like domain that functions to regulate dendritic arborization and dendritic spine type in hippocampal neurons
Jayashree Kadirvelu, Savannah E. Jacobs, Ruochuan Liu, Antoinette J. Charles, Jun Yin, Angela M. Mabb
This study identifies a domain in RNF216 that regulates dendritic arborization and spine morphology through ubiquitin chain assembly, independent of its catalytic activity.
bioRxiv · Oct 19, 2023 · PreprintNeuroscience