Author

Savannah E. Jacobs

Georgia State UniversityORCID 0009-0002-9172-4495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Angela M. MabbiD· 2 shared Jun YiniD· 2 shared Antoinette J. CharlesiD· 1 shared Bo ZhaoiD· 1 shared Bradley R. Kossmann· 1 shared Duc Minh DuongiD· 1 shared Geng CheniD· 1 shared Geon Ho Jeong· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Angela M. MabbORCID

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2 papers

Recent·Most cited

BiochemistryiSciencePeer-reviewedJun 17, 2025

Engineering a Cell-Based Orthogonal Ubiquitin Transfer Cascade for Profiling the Substrates of RBR E3 Parkin

Shuai Fang, Li Zhou, Geng Chen…·Jun Yin

This study develops an orthogonal ubiquitin transfer cascade to profile Parkin substrates, revealing roles in DNA replication, protein transport, and mitophagy.

4 citations

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 19, 2023

The E3 ubiquitin ligase RNF216 contains a linear ubiquitin chain-determining-like domain that functions to regulate dendritic arborization and dendritic spine type in hippocampal neurons

Jayashree Kadirvelu, Savannah E. Jacobs, Ruochuan Liu…·Angela M. Mabb

This study identifies a domain in RNF216 that regulates dendritic arborization and spine morphology through ubiquitin chain assembly, independent of its catalytic activity.

1 citation

mouseexperimental assay

𝕏 PostBluesky