Author

Jean M. Macklaim

DNA Genotek (Canada)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Brice Le FrançoisiD· 2 shared Daryl M. GohliD· 2 shared Alaya Mikalauskas· 1 shared Amanda K. CertanoiD· 1 shared Anne Bouevitch· 1 shared Asako Tan· 1 shared Benjamin AuchiD· 1 shared Christina G. FrageliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Brice Le FrançoisORCID

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Author profile →

3 papers

Recent·Most cited

Vaginal metatranscriptome meta-analysis reveals functional BV subgroups and novel colonisation strategies

Scott J Dos Santos, Clara Copeland, Jean M. Macklaim, Gregor Reid, Gregory Brian Gloor

This study analyzes vaginal metatranscriptomes to identify functional subgroups and microbial strategies in bacterial vaginosis, highlighting functional differences over taxonomic ones.

Microbiome · Dec 21, 2024Peer-reviewedMicrobiology

Rational probe design for efficient rRNA depletion and improved metatranscriptomic analysis of human microbiomes

Asako Tan, Senthil K. Murugapiran, Alaya Mikalauskas, Jeff Koble, Drew Kennedy, Fred W. Hyde, Victor Ruotti, Emily Law, Jordan Jensen, Gary P. Schroth, Jean M. Macklaim, Scott Kuersten, Brice Le François, Daryl M. Gohl

The paper introduces a probe set for efficient rRNA depletion in human microbiome samples, improving metatranscriptomic analysis and reducing quantitative error.

BMC Microbiology · Oct 20, 2023Peer-reviewedGenomics

Dissecting and Tuning Primer Editing by Proofreading Polymerases

Daryl M. Gohl, Benjamin Auch, Amanda K. Certano, Brice Le François, Anne Bouevitch, Evgueni Doukhanine, Christina G. Fragel, Jean M. Macklaim, Emily B. Hollister, John Garbe, Kenneth B. Beckman

The paper develops synthetic DNA standards to measure primer editing by proofreading polymerases and shows it can be tuned to improve microbiome profiling.

Nucleic Acids Research · May 17, 2021Peer-reviewedMolecular Biology