Asako Tan

RiboZAP: Custom probe design for rRNA depletion in complex metatranscriptomes

RiboZAP designs custom rRNA depletion probes from metatranscriptomic data without prior knowledge of sample composition, improving mRNA recovery and transcriptome coverage.

Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences

The paper improves rRNA depletion for mouse cecal metatranscriptome analysis by designing probes based on sequence abundance rather than taxonomy, increasing mRNA reads and reducing bias.

Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain

The paper studies how different introns respond to splicing inhibitors in a humanized yeast strain, revealing intron-specific sensitivity and the impact of BP sequence variation.

Rational probe design for efficient rRNA depletion and improved metatranscriptomic analysis of human microbiomes

The paper introduces a probe set for efficient rRNA depletion in human microbiome samples, improving metatranscriptomic analysis and reducing quantitative error.

Prediction of Fine-tuned Promoter Activity from DNA Sequence

This paper develops a model to predict promoter activity from DNA sequence, achieving high accuracy in predicting natural variants compared to lab-mutated ones.