Author

Jeannette Comte

Children's Hospital Research Institute of Manitoba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew J. HalaykoiD· 2 shared Chinonye Doris OnuzuluiD· 2 shared Christopher D. PascoeiD· 2 shared Maria Shenna Fauni· 2 shared Meaghan J. JonesiD· 2 shared Nikho A Hizon· 2 shared Samantha A. LeeiD· 2 shared Shivam ChadhaiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Andrew J. HalaykoORCID

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2 papers

Recent·Most cited

Novel DNA methylation changes in mouse lungs associated with heavy smoking

Chinonye Doris Onuzulu, Samantha A. Lee, Sujata Basu, Jeannette Comte, Yan Hai, Nikho A Hizon, Shivam Chadha, Maria Shenna Fauni, Andrew J. Halayko, Christopher D. Pascoe, Meaghan J. Jones

This study identifies 32 differentially methylated genes in mouse lungs associated with heavy smoking, revealing novel links to nicotine dependency, tumorigenesis, and COPD.

bioRxiv · Nov 6, 2023 · PreprintMolecular Biology

Early life exposure to cigarette smoke primes lung function changes and DNA methylation changes at Cyp1a1 upon exposure later in life

Chinonye Doris Onuzulu, Samantha A. Lee, Sujata Basu, Jeannette Comte, Yan Hai, Nikho A Hizon, Shivam Chadha, Maria Shenna Fauni, Shana Kahnamoui, Bo Xiang, Andrew J. Halayko, Vernon Wayne Dolinsky, Christopher D. Pascoe, Meaghan J. Jones

This study shows that prenatal and early postnatal cigarette smoke exposure in mice leads to long-term lung function and DNA methylation changes at Cyp1a1, which can be reestablished upon adult re-exposure.

bioRxiv · Mar 3, 2023 · PreprintGenetics