Meaghan J. Jones

This study examines how prenatal air pollution exposure affects DNA methylation in cord blood and its link to childhood wheeze, finding some epigenetic changes are partially buffered by maternal diet.

This study develops epigenetic clocks for three large mammals using DNA methylation data to estimate age with high accuracy and robustness.

This study links climate change to accelerated epigenetic aging in polar bears, reduced fitness, and near-zero adaptive potential.

This study identifies 32 differentially methylated genes in mouse lungs associated with heavy smoking, revealing novel links to nicotine dependency, tumorigenesis, and COPD.

This study shows that prenatal and early postnatal cigarette smoke exposure in mice leads to long-term lung function and DNA methylation changes at Cyp1a1, which can be reestablished upon adult re-exposure.

This study identifies persistent DNA methylation changes linked to prenatal NO2 exposure in early childhood and links some changes to wheeze and atopy.

The paper evaluates and validates reference and library selection methods for deconvolving cord blood DNA methylation data, finding that the IDOL library outperforms automatic selection methods.

The paper examines how genetic and environmental factors influence DNA methylation at variably methylated regions in neonatal blood, finding that combined effects best explain methylation variability.

The paper examines DNA methylation differences in white blood cell types between newborn and adult blood, showing how these changes reflect immune maturation and affect cell type prediction accuracy.

BECon provides metrics to interpret blood-based DNA methylation results in the context of brain tissue using paired blood and brain samples.