A Pan-Beta-Coronavirus Vaccine Bearing Conserved and Asymptomatic B- and T-Cell Epitopes Protect Against Highly Pathogenic Delta and Highly Transmissible Omicron SARS-CoV-2 Variants of Concern.
Hawa Vahed, Swayam Prakash, Afshana Quadiri, Izabela Coimbra Ibraim, Etinosa Omorogieva, Swena Patel, Jimmy Tadros, Emma Jane Liao, Lauren Lau, Aziz Alami Chentoufi, Anthony B. Nesburn, Baruch D. Kuppermann, Jeffrey B. Ulmer, Daniel Gil, Lbachir BenMohamed
This paper develops a multi-epitope vaccine targeting conserved B- and T-cell epitopes from SARS-CoV-2, showing protection against Delta and Omicron variants in a mouse model.
Human Vaccines & Immunotherapeutics · Jul 4, 2025Peer-reviewedImmunology