Hawa Vahed

A Pan-Beta-Coronavirus Vaccine Bearing Conserved and Asymptomatic B- and T-Cell Epitopes Protect Against Highly Pathogenic Delta and Highly Transmissible Omicron SARS-CoV-2 Variants of Concern.

This paper develops a multi-epitope vaccine targeting conserved B- and T-cell epitopes from SARS-CoV-2, showing protection against Delta and Omicron variants in a mouse model.

CXCL13/CXCR5 Chemokine Axis Promotes CXCR5+CD19+ B-Cell and Follicular/Effector CXCR5+CD4+ T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta Variant

This study shows that CXCL13 deficiency in mice worsens SARS-CoV-2 infection, with higher viral load, lung damage, and reduced B and T cell responses.

Tissue-Targeted Prime/Pull/Keep Therapeutic Herpes Simplex Virus Vaccine Protect Against Recurrent Ocular Herpes Diseases in HLA-A*0201 Transgenic Rabbits

This study tests a prime/pull/keep HSV-1 vaccine in HLA-A*0201 transgenic rabbits, showing it reduces corneal herpes infection by mobilizing and retaining CD8+ T cells in infected tissues.

Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19

This study identifies conserved B-cell epitopes on the SARS-CoV-2 Spike protein that elicit strong neutralizing antibodies and provide protection against the Delta variant in a mouse model.

Spike mRNA Vaccine Encapsulated in a Lipid Nanoparticle Composed of Phospholipid 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine Induced Potent B- and T-cell Responses Associated with Protection against COVID-19 in Hamsters

This study shows that a specific lipid nanoparticle formulation enhances B- and T-cell responses and provides better protection against SARS-CoV-2 in hamsters.