Error-corrected Duplex Sequencing enables direct detection and quantification of mutations in human TK6 cells with remarkable inter-laboratory consistency
Eunnara Cho, Carol D. Swartz, Andrew Williams, Miriam V. Rivas, Leslie Recio, Kristine L. Witt, Elizabeth K. Schmidt, Jeffry Yaplee, Thomas Horace Smith, Phu Van, Fang Yin Lo, Charles C. Valentine, Jesse J. Salk, Francesco Marchetti, Stephanie L. Smith‐Roe, Carole Lyn Yauk
This study demonstrates that error-corrected Duplex Sequencing reliably detects and quantifies mutations in human TK6 cells across different laboratories and time points.
bioRxiv · Feb 22, 2023 · PreprintGenomics