Exploring GPCR-mediated optogenetic modulation of seizure network in a pig model of Temporal Lobe Epilepsy
Su-Youne Chang, Karni Lev Bar-Or, Filip Mívalt, Daniela D. Maltais, Yoav Kfir, Jiwon W. Kim, Inyong Kim, Matan Hershko, Jenn Daily, Evyatar Swissa, Ofir Levi, Sasha Devore, Ofer Yizhar, Yotam Eldar, Gregory A. Worrell
This study evaluates eOPN3, a red-shifted inhibitory opsin, in a pig model of Temporal Lobe Epilepsy to modulate seizure activity using optogenetics.
bioRxiv · Jan 23, 2025 · PreprintNeuroscience