Reassessment of RNF43 Function Reveals No Impact on Endogenous EGFR or BRAF Protein Stability
Jiahui Niu, Shanshan Li, Ruyi Zhang, Jenna van Merode, Maikel Petrus Peppelenbosch, Ron Smits
This study investigates whether RNF43 regulates EGFR or BRAF protein stability and finds no consistent evidence of such regulation, contradicting recent reports.
bioRxiv · Mar 20, 2026 · PreprintCell Biology