Author

Ron Smits

Erasmus MCORCID 0000-0001-6798-3206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jenna van Merode· 2 shared Jiahui NiuiD· 2 shared Maikel Petrus PeppelenboschiD· 2 shared Ruyi ZhangiD· 2 shared Shanshan Li· 2 shared Lisa van de Kamp· 1 shared Madalena Neves Cabrita· 1 shared Nicky de Schipper· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Jenna van Merode

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 20, 2026

Reassessment of RNF43 Function Reveals No Impact on Endogenous EGFR or BRAF Protein Stability

Jiahui Niu, Shanshan Li, Ruyi Zhang…·Ron Smits

This study investigates whether RNF43 regulates EGFR or BRAF protein stability and finds no consistent evidence of such regulation, contradicting recent reports.

DOI 10.64898/2026.03.18.712374

humanproteomics

𝕏 PostBluesky

Cancer BiologyOncogenePeer-reviewedDec 14, 2024

Lack of dominant-negative activity for tumor-associated ZNRF3 missense mutations at endogenous expression levels

Shanshan Li, Jiahui Niu, Ruyi Zhang…·Ron Smits

This study shows that tumor-associated ZNRF3 missense mutations do not exhibit dominant-negative activity and instead act as loss-of-function mutations at endogenous levels.

8 citations

humanprotein structure

𝕏 PostBluesky