Maikel Petrus Peppelenbosch

This study investigates whether RNF43 regulates EGFR or BRAF protein stability and finds no consistent evidence of such regulation, contradicting recent reports.

This study evaluates denifanstat's effects on HEV replication and inflammatory responses in steatotic liver organoids and macrophages, finding moderate antiviral activity in macrophages but not in organoids.

This study shows that tumor-associated ZNRF3 missense mutations do not exhibit dominant-negative activity and instead act as loss-of-function mutations at endogenous levels.