Developmental priming increases copper-tolerance in a model fish species via epigenetic-and microbiome-mediated mechanisms
Tamsyn M. Uren Webster, Lauren V. Laing, Jemima Onime, Hannah R. Littler, Rob J. McFarling, Josephine R. Paris, Jennifer A. Fitzgerald, Anke Lange, Audrey Farbos, Karen Moore, Matthew D. Hitchings, Ronny van Aerle, Nicolas R. Bury, Eduarda M. Santos
This study shows that developmental priming with low copper exposure increases copper tolerance in stickleback fish through epigenetic and microbiome changes.
bioRxiv · Nov 28, 2025 · PreprintEvolutionary Biology