Superinfection with intact HIV-1 results in conditional replication of defective proviruses and nonsuppressible viremia in people living with HIV-1
Vivek Hariharan, Jennifer A. White, Filippo Dragoni, Emily J. Fray, Nicholas M. Pathoulas, Milica Moskovljevic, Hao Zhang, Anushka Singhal, Jun Lai, Subul A. Beg, Eileen P. Scully, Elizabeth A. Gilliams, David S. Block, Jeanne C. Keruly, Richard D. Moore, , Robert F. Siliciano
The paper investigates superinfection with intact HIV-1 in people living with HIV-1, showing it leads to conditional replication of defective proviruses and nonsuppressible viremia.
Nature Microbiology · Oct 3, 2025Peer-reviewedMicrobiology