Author

Michael S. Kareta

Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0002-6980-9065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alicia Simmons· 1 shared Anish ThomasiD· 1 shared Anthony Nicholas KarnezisiD· 1 shared Chongyuan LuoiD· 1 shared Godfrey A. DzhivhuhoiD· 1 shared Howard Y. ChangiD· 1 shared Indra ChandrasekariD· 1 shared Jae‐Il ParkiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperDevelopmental Biology

Alicia Simmons

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SMARCA4 is essential for early-stage tumor development but its loss promotes late-stage cancer progression in small-cell lung cancer

Nicole A. Kirk, Jin Ng, Kate-Lin Ly, Young Ho Ban, Godfrey A. Dzhivhuho, Jinho Jang, Kyung-Pil Ko, Michael S. Kareta, Jae‐Il Park, Anthony Nicholas Karnezis, Anish Thomas, Kate D. Sutherland, Kwon-Sik Park

This study shows SMARCA4 is important for early tumor development in SCLC but its loss promotes late-stage cancer progression through altered tumor-NK cell interactions.

bioRxiv · May 21, 2025 · PreprintCancer Biology

Kidney collecting duct cell type composition is regulated by Notch signaling via modulation of mTORC1

Jennifer deRiso, Malini Mukherjee, Madhusudhana R. Janga, Alicia Simmons, Michael S. Kareta, Jianning Tao, Indra Chandrasekar, Kameswaran Surendran

This study identifies Hes1 as a Notch signaling target that regulates mTORC1 activity to maintain distinct epithelial cell types in kidney collecting ducts.

bioRxiv · Apr 9, 2024 · PreprintDevelopmental Biology

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

Chongyuan Luo, Qian Yi Lee, Orly L. Wapinski, Rosa Castanon, Joseph R. Nery, Moritz Mall, Michael S. Kareta, Sean M. Cullen, Margaret A. Goodell, Howard Y. Chang, Marius Wernig, Joseph R. Ecker

This study examines DNA methylation changes during fibroblast-to-neuron reprogramming, identifying key factors and mechanisms involved in epigenomic remodeling.

eLife · Jan 14, 2019Peer-reviewedNeuroscience