ImmunologybioRxivPreprint
A hypermorphic Nfkbid allele represents an Idd7 locus gene contributing to impaired thymic deletion of autoreactive diabetogenic CD8+ T-cells in NOD mice.
Maximiliano Presa, Jeremy J. Racine, Jennifer R. Dwyer…·David V. Serreze
This study identifies a hypermorphic Nfkbid allele at the Idd7 locus that impairs thymic deletion of autoreactive CD8+ T-cells in NOD mice, contributing to type 1 diabetes development.
DOI 10.1101/249094