A Multiparametric Activity Profiling Platform for Neuron Disease Phenotyping and Drug Screening
Bruno Boivin, Kasper C. D. Roet, Xuan Huang, Kyle W. Karhohs, Mohammad Hossein Rohban, Jackson Sandoe, Ole Wiskow, Rie K. Maeda, Alyssa Grantham, Mary Kate Dornon, Jenny Shao, Devlin Frost, Dylan S. Baker, Kevin C. Eggan, Anne Elizabeth Carpenter, Clifford J. Woolf
The paper introduces a cloud-based platform for analyzing calcium activity in motor neurons to identify compounds that reverse disease phenotypes in amyotrophic lateral sclerosis.
Molecular Biology of the Cell · Dec 15, 2021Peer-reviewedNeuroscience