Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen
Ryan S. McCool, Cory M. Acreman, Abigail E. Powell, Sofia I. Picucci, Daniel J Stieh, Jeremy Huynh, Hannah Caruso, Soyoon Park, Jessica O’Rear, Jui‐Lin Chen, Brad A. Palanski, Patrick O. Byrne, Madeline R. Sponholtz, Chia‐Wei Chou, Jeongryeol Kim, , Jason S. McLellan
This study designs and characterizes a prefusion-stabilized EBV gB antigen, showing improved immunogenicity and structural insights for vaccine development.
bioRxiv · May 19, 2025 · PreprintBiochemistry